Companies
Organizations producing, processing, enriching, and commercializing isotopes across medicine, energy, quantum materials, and industry.
Content reviewed August 2026. Production nodes update when capacity or status changes.
The commercial layer
Companies turn isotope production into usable supply. Some enrich. Some manufacture medical products. Some build the machines and processing systems that make production possible.
This page is a role map, not a ranking. For financing structure, use Capital & Markets. For external directories and institutions, use Links.
Production & Enrichment
ASP Isotopes
PublicEnrichmentAdvanced materialsPublic company developing enrichment processes for high-value stable isotopes used in advanced materials and related markets.
Focus: Stable isotope enrichment pathways for quantum, semiconductor, medical, and industrial materials.
Quantum Leap Energy
Fuel cycleConversionHALEUASP Isotopes subsidiary focused on nuclear fuel-cycle pathways, including uranium conversion work, HALEU-oriented enrichment efforts, and lithium isotope separation.
Focus: Uranium conversion, advanced enrichment pathways, and lithium isotopes.
Note: Fuel-cycle company under the ASP Isotopes group, not a medical radiopharma manufacturer.
Silex Systems
PublicLaser enrichmentAustralian public company developing laser isotope separation technology across enrichment pathways.
Focus: Laser isotope separation technology development.
Centrus Energy
PublicUranium enrichmentHALEUU.S. enrichment company central to domestic High-Assay Low-Enriched Uranium capacity and broader nuclear fuel enrichment infrastructure.
Focus: Uranium enrichment and HALEU production capacity.
Note: Key public reference point in the U.S. enrichment rebuild.
Urenco
EnrichmentCommercialMajor commercial uranium enricher with centrifuge plants in Europe and the United States.
Focus: Industrial uranium enrichment capacity.
Orano
Fuel cycleEnrichmentFuel-cycle company with major commercial enrichment capacity and broader nuclear services.
Focus: Enrichment and nuclear fuel-cycle operations.
ConverDyn
ConversionUF6U.S. uranium conversion joint venture context tied to UF6 feedstock supply ahead of enrichment.
Focus: Uranium conversion to enrichment feedstock.
BWX Technologies
PublicNuclear manufacturingNuclear manufacturing company with roles across naval nuclear, commercial nuclear components, and selected isotope-related production activities.
Focus: Nuclear manufacturing and specialty isotope-linked capacity.
Framatome
Nuclear fuelTechnologyNuclear fuel and technology company active across fuel fabrication and related nuclear systems.
Focus: Nuclear fuel systems and advanced fuel-cycle support.
Westinghouse
Co-60Power reactorTechnologyNuclear technology company developing pressurized water reactor methods for cobalt-60 production in partnership with source manufacturers. Extends Co-60 production beyond traditional CANDU routes into the broader PWR fleet.
Focus: PWR-compatible Co-60 production technology and deployment with utility partners for domestic and scalable supply.
Note: Important for the industrial isotope layer. Moves Co-60 production into reactor types that dominate the global power fleet.
Eckert & Ziegler
PublicIsotope productsEstablished supplier of isotope products, components, and related systems for medical and industrial users.
Focus: Commercial isotope products and radiopharmaceutical support systems.
IBA
PublicCyclotronsMajor provider of cyclotron and radiopharma production systems used in medical isotope infrastructure worldwide.
Focus: Cyclotrons and radiopharmaceutical production infrastructure.
China Isotope & Radiation Corporation
PublicIsotope productionMajor Chinese isotope and radiation company involved in production and radiopharmaceutical-related supply.
Focus: Isotope production and radiation applications at scale.
Medical & Radiopharmaceutical
Novartis
PublicRadioligand therapyMajor pharmaceutical company with radioligand therapy programs that depend on reliable therapeutic isotope supply.
Focus: Radioligand therapeutics and clinical nuclear medicine platforms.
Bayer
PublicTargeted therapyPharmaceutical company with targeted radiotherapy products in the nuclear medicine landscape.
Focus: Targeted radiotherapeutic products and related clinical platforms.
Lantheus
PublicDiagnosticsTherapeuticsCommercial nuclear medicine company active in diagnostic imaging agents and therapeutic development.
Focus: Diagnostic and therapeutic radiopharmaceutical products.
Telix Pharmaceuticals
PublicRadiopharmaRadiopharmaceutical company developing diagnostic and therapeutic agents across oncology and related indications.
Focus: Targeted radiopharmaceutical diagnostics and therapy.
Curium
Medical isotopesManufacturingLarge nuclear medicine manufacturer and supplier supporting diagnostic and therapeutic isotope products.
Focus: Medical isotope manufacturing and radiopharmaceutical supply.
ITM Isotope Technologies Munich
TheranosticsProductionEuropean radiopharmaceutical and isotope company focused on targeted radionuclide therapy and related production capability.
Focus: Therapeutic radioisotopes and theranostic development.
NorthStar Medical Radioisotopes
Mo-99Production technologyU.S. company developing alternative production routes for molybdenum-99 and related medical isotope supply technology.
Focus: Mo-99 production technology and medical isotope manufacturing systems.
SHINE Technologies
Production technologyMedicalCompany developing alternative production systems for medical isotopes and related nuclear technology applications.
Focus: Alternative medical isotope production technology.
Nusano
Accelerator productionAccelerator-based isotope production company building capacity for medical and related radioisotopes.
Focus: Accelerator production platforms for radioisotopes.
TerraPower Isotopes
Ac-225ManufacturingExpanding actinium-225 supply for targeted alpha therapy, including a large cGMP manufacturing project in Philadelphia intended to raise capacity once online.
Focus: Ac-225 production scale-up for advanced cancer therapies.
Note: Planned capacity expansion. Not the same as TerraPower's reactor business.
PanTera
Ac-225ProductionCompany focused on actinium-225 production scale-up for targeted alpha therapy supply.
Focus: Ac-225 production capacity.
Niowave
AcceleratorAc-225Accelerator-based medical isotope company active in actinium-225 and related radioisotope pathways.
Focus: Accelerator production of medical radioisotopes.
Cardinal Health
TheranosticsAc-225DistributionMajor nuclear medicine and theranostics supply actor. Its Center for Theranostics Advancement supports commercial-scale radiopharmaceutical production and distribution, including actinium-225 related capacity growth.
Focus: Radiopharmaceutical manufacturing, theranostics supply, and last-mile nuclear medicine logistics.
Note: Important to the Ac-225 and broader therapeutic isotope commercial chain, especially where production volume and distribution meet.
Orano Med
Alpha therapyPb-212Orano's nuclear medicine arm focused on targeted alpha therapy and related isotope development.
Focus: Targeted alpha therapy isotope platforms.
Isotopia
TherapeuticsProductionRadiopharmaceutical and isotope company active in therapeutic isotope development and supply.
Focus: Therapeutic radioisotope products.
SOFIE
PETManufacturingRadiopharma company connected to PET manufacturing and broader nuclear medicine supply activity.
Focus: PET radiopharmaceutical manufacturing.
ARTMS
Cyclotron technologyTechnology company focused on cyclotron-based production routes for medical isotopes.
Focus: Cyclotron production technology for medical isotopes.
Nordion
Co-60MedicalIndustrialMajor commercial processor and supplier in the cobalt-60 chain. Finished Co-60 sources for sterilization and selected medical uses depend on upstream power-reactor irradiation plus specialized source fabrication and distribution.
Focus: Co-60 supply for medical device sterilization, industrial irradiation, and related medical applications, tied to power-reactor production partners.
Note: Concentration point in the Co-60 network. Power-reactor harvest capacity and source processing both matter.
National & Regional Producers
IRE
MedicalMo-99Belgian radioisotope producer important to global molybdenum-99 and related medical isotope supply.
Focus: Reactor-linked medical radioisotope production.
NTP Radioisotopes
MedicalMo-99South African radioisotope producer linked to SAFARI-1 production pathways.
Focus: Medical radioisotope production and supply.
ANSTO
National labMedicalAustralian nuclear science organization with reactor-based radioisotope production through OPAL-related pathways.
Focus: National radioisotope production and nuclear science services.
NRG
IrradiationPettenOperator context around the Petten research reactor and related irradiation services important to European isotope supply.
Focus: Research reactor irradiation and isotope-related services.
POLATOM
MedicalPolandPolish radioisotope producer linked to MARIA reactor pathways.
Focus: National radioisotope production and supply.
INVAP
Reactor technologyArgentinaArgentine nuclear technology company connected to research reactor and isotope infrastructure development.
Focus: Research reactor technology and related nuclear infrastructure.
KAERI
National labKoreaKorea Atomic Energy Research Institute context around HANARO and national nuclear research capacity.
Focus: National nuclear research and irradiation capability.
JSC Isotope
SupplyRussiaRussian isotope trading and supply organization connected to national production capacity.
Focus: Isotope supply organization linked to domestic production nodes.
Strategic & Nuclear Supply
DOE Isotope Program
U.S. programNational labsU.S. program coordinating isotope production and distribution across national laboratory capabilities.
Focus: Strategic research and specialty isotope availability.
Note: Infrastructure network rather than a single commercial producer.
Wider commercial landscape
For broader public and private directories, institutions, and data sources, use the Links page.
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